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San Diego Blood Bank is bringing greater precision to transfusion medicine through DNA Analysis.
There are over 100 blood groups in humans, and an individual person belongs to one blood type in each of these groups. When chronic transfusion patients receive blood, donors and recipients are matched based on their A, B, O, and Rh- or Rh+ blood types. The goal is to avoid “anti-self” responses by the patient’s immune system, which can lead to potentially fatal clumping of blood cells.
Patients who receive multiple transfusions – such as leukemia patients, other cancers, kidney disease, bone marrow disorders, and sickle cell disease, are at risk for adverse transfusion responses.
San Diego Blood Bank envisions a new standard of care…
Today, San Diego Blood Bank will implement the next generation DNA analysis to genotype our donors to more precisely match their blood donations with their patient recipients.
This information ensures that a patient who needs a blood transfusion is
more precisely matched to the recipient to reduce the risk of complications.
This approach takes into account individual variability in genes for each patient and aligns with precision medicine to allow SDBB, physicians and researchers to predict more accurately the best treatment strategies for transfusion patients.
SDBB will partner with hospitals to measure clinical results and to ensure excellent patient outcomes.